abstract：:The enthusiasm for evidence-based medicine (EBM) has not been accompanied by the same success in bridging the gap between theory and practice. This paper advances the hypothesis that the phenomenon psychologists call hypocognition may hinder the development of EBM. People tend to respond to frames rather than to facts...

journal_title：Internal medicine journal

authors： Mariotto A

更新日期：2010-01-01 00:00:00

abstract：:Depression is the leading cause of non-fatal disease burden in Australia. Recently, increasing public recognition, together with the development of more integrated medical and psychological healthcare services has resulted in significant improvements. New pathophysiological models incorporate structural brain changes ...

journal_title：Internal medicine journal

authors： Hickie IB,Naismith SL,Norrie LM,Scott EM

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Unrelated umbilical cord blood has emerged as an alternative stem cell source for allogeneic transplantation for patients with haematological malignancies, but in adults is limited by the low number of stem cells present in banked cord blood units. We report our experience with double cord blood transplants ...

journal_title：Internal medicine journal

authors： Bradstock K,Hertzberg M,Kerridge I,Svennilson J,George B,McGurgan M,Huang G,Antonenas V,Gottlieb D

更新日期：2009-11-01 00:00:00

abstract：:Diabetes mellitus (DM) has been found to be associated with cardiovascular disease. The goal of this study is to evaluate the prevalence of asthma in patients with type II DM after adjusting for other comorbid conditions. We used patient treatment files of inpatients' admissions containing discharge diagnosis (Classif...

journal_title：Internal medicine journal

authors： Hashemzadeh M,Movahed MR

更新日期：2009-10-01 00:00:00

abstract：:More than 177 000 potentially preventable healthcare-associated infections (HAIs) occur per annum in Australia with sizable attributable mortality. Organizational systems to protect against HAI in hospitals in Australia are relatively poorly developed. Awareness and practice of infection control by medical and other h...

journal_title：Internal medicine journal

authors： Ferguson JK

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Since 1995 patients with relapsed aggressive non-Hodgkin lymphoma have been treated with high-dose chemotherapy (HDC) instead of standard dose chemotherapy (SC) because of superior survival shown in the 'Parma study'. As HDC involves hospital admission and intensive supportive care, the cost of HDC would be ...

journal_title：Internal medicine journal

authors： Prajogo J,Neil A,Duke J,Zhang H,Stokes B,Rowlings P

更新日期：2009-08-01 00:00:00

abstract：:Imatinib mesylate (IM) is currently used as the first therapeutic choice against chronic myelogenous leukaemia (CML). Because IM poorly penetrates the blood-brain barrier, IM-treated CML patients may have a potential risk of central nervous system (CNS) involvement. Here we report a case with lymphoid blast crisis iso...

journal_title：Internal medicine journal

authors： Isobe Y,Sugimoto K,Masuda A,Hamano Y,Oshimi K

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Medical school and resident training programmes offer different learning opportunities and outcomes. The aim of the study was to assess medical student and intern experience in common clinical procedures. METHODS:Interns employed in a metropolitan teaching hospital from 2000 to 2004 completed a survey of ex...

journal_title：Internal medicine journal

authors： Boots RJ,Egerton W,McKeering H,Winter H

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The use of contrast agents during coronary intervention can result in nephropathy, particularly in patients with renal dysfunction. We aimed to determine whether the use of iso-osmolar iodixanol is less nephrotoxic than that of low-osmolar iopromide when patients are adequately prehydrated and have received ...

journal_title：Internal medicine journal

authors： Juergens CP,Winter JP,Nguyen-Do P,Lo S,French JK,Hallani H,Fernandes C,Jepson N,Leung DY

更新日期：2009-01-01 00:00:00

abstract：:Depression, ischaemic heart disease and cerebrovascular disease are important causes of morbidity and are among the leading contributors to global health burden. These conditions often occur in the same patient, resulting in considerably greater effect on health than combinations of chronic diseases without depression...

journal_title：Internal medicine journal

authors： Ziegelstein RC,Parakh K,Sakhuja A,Bhat U

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Pleural procedures may cause serious complications when incorrectly carried out. There is a need to find effective methods for teaching how to insert a chest drain safely. AIM:To assess the effectiveness of a programme for teaching chest tube insertion using a simulation model (SuperAnnie). METHODS:Groups ...

journal_title：Internal medicine journal

authors： Hutton IA,Kenealy H,Wong C

更新日期：2008-12-01 00:00:00

abstract：:Based on the number of new cases (incidence), non-Hodgkin lymphoma is an increasingly common cancer in Australia and many developed countries. Until recently, mortality trends have been stable or slightly increasing. However, since the year 2000, mortality has decreased every year by an average of 5.1% per year (95% c...

journal_title：Internal medicine journal

authors： Coory M,Gill D

更新日期：2008-12-01 00:00:00

abstract：:Abstract Hyperammonaemic encephalopathy has been infrequently reported after both standard and high-dose chemotherapy for solid and haematological malignancies. It is important to consider this diagnosis for patients with unexplained behaviour changes or encephalopathy and this case report emphasizes this condition an...

journal_title：Internal medicine journal

authors： Nott L,Price TJ,Pittman K,Patterson K,Young R,Fletcher J

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:The aim of the study was to assess the structural and functional effects of autologous stem cell transplantation (ASCT) on scleroderma finger clawing. METHODS:Using photocopies of hands of five scleroderma patients who underwent ASCT using photocopies of hands. Functional assessments used a standardized que...

journal_title：Internal medicine journal

authors： Englert H,Kirkham S,Moore J,Poon TS,Katelaris C,McGill N,Schrieber L,Manolios N

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Informed consent is a mainstay of clinical practice, with both moral and legal forces. Material disclosure about extreme treatments, however, is unlikely to convey the full impact of the experience of treatment. Informed consent may be flawed under such circumstances. The aims of this study were to compare e...

journal_title：Internal medicine journal

authors： Little M,Jordens CF,McGrath C,Montgomery K,Lipworth W,Kerridge I

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The elderly obese are at increased risk of mortality and morbidity of many obesity-related chronic diseases, such as hypertension, diabetes and coronary heart disease. This study was designed to investigate the epidemiological features of overweight and obesity in older rural Chinese. METHODS:A cross-sectio...

journal_title：Internal medicine journal

authors： Zhang X,Sun Z,Zhang X,Zheng L,Liu S,Xu C,Li J,Zhao F,Li J,Hu D,Sun Y

更新日期：2008-07-01 00:00:00

abstract：:Climate change is unequivocal. The fourth assessment report of the Intergovermental Panel on Climate Change has recently projected that global average surface temperature will increase by 1.1 to 6.4 degrees C by 2100. Anthropogenic warming during the twenty-first century would be much greater than that observed in the...

journal_title：Internal medicine journal

authors： Tong S,Mackenzie J,Pitman AJ,FitzGerald G,Nicholls N,Selvey L

更新日期：2008-06-01 00:00:00

abstract：:Antifungal prophylaxis can be recommended in patients undergoing induction chemotherapy for acute myeloid leukemia and treatment for grade 2 or greater or chronic extensive graft versus host disease. The evidence for prophylaxis is less clear in other clinical settings although certain groups such as patients with pro...

journal_title：Internal medicine journal

authors： Slavin MA,Heath CH,Thursky KA,Morrissey CO,Szer J,Ling LM,Milliken ST,Grigg AP

更新日期：2008-06-01 00:00:00

abstract：:This review summarises the available clinical trials data investigating the effects of glucose lowering on mortality in patients admitted to hospital with acute myocardial infarction. The results of these studies are inconclusive with no clear evidence that this intervention has additional benefit over and above routi...

journal_title：Internal medicine journal

authors： Braatvedt GD

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Poor quality prescribing has been identified as one of the leading causes of medication error and adverse drug events. The aim of this study was to improve the quality of written prescriptions in a general hospital by a combination of serial audits and interventions designed to address identified deficiencie...

journal_title：Internal medicine journal

authors： Gommans J,McIntosh P,Bee S,Allan W

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:There are several treatment modalities available for diabetes; however, the effects of the different medications on coronary artery disease are less understood. The purpose of this study was to evaluate the correlation of insulin-sensitizing therapy with the outcome of stress myocardial perfusion testing and...

journal_title：Internal medicine journal

authors： Kapinya K,Nijjar PS,Stanek M,Amanullah A

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The altered status of iron metabolism is reported in hereditary haemochromatosis and in non-alcoholic liver fatty disease. We investigated the relation between the H63D HFE mutation gene and non-alcoholic steatohepatitis (NASH). METHODS:We studied as outpatients, 272 Italian persons with NASH and compared t...

journal_title：Internal medicine journal

authors： Neri S,Pulvirenti D,Signorelli S,Ignaccolo L,Tsami A,Mauceri B,Misseri M,Interlandi D,Cutuli N,Castellino P

更新日期：2008-04-01 00:00:00

abstract：:Autologous stem cell transplantation (ASCT) has a well-established role in the treatment of haematological malignancies. Stem cells are commonly collected following salvage chemotherapy although there may be advantages in collecting earlier in the disease course. A 'rainy day' harvest (RDH) refers to the collection of...

journal_title：Internal medicine journal

authors： Trotman J,Presgrave P,Kwan Y,Tiley C,Estell J,Watson AM,O'Brien TA,Peters D

更新日期：2008-04-01 00:00:00

abstract：:Neuroimaging in dementia has focused on documenting any burden of vascular disease or excluding any reversible intracranial pathology. We review the use of computed tomography to examine for medial temporal lobe atrophy in dementia and compare this with a case series of such measurements from our memory clinic. Measur...

journal_title：Internal medicine journal

authors： Rose M,Scharf S

更新日期：2008-02-01 00:00:00

abstract：AIMS:The aim of this study was to provide the first population-based descriptions of typical sleep duration and the prevalence of chronic sleep restriction and chronic sleepiness in community-dwelling Australian adults. METHODS:Ten thousand subjects randomly selected from the New South Wales electoral roll, half aged ...

journal_title：Internal medicine journal

authors： Bartlett DJ,Marshall NS,Williams A,Grunstein RR

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Populations with increased skin pigmentation who have migrated to countries of high latitude are at increased risk of low vitamin D. This study aimed to determine the prevalence of low vitamin D among the refugee population arriving in New Zealand. METHODS:An audit of all refugees arriving at the national r...

journal_title：Internal medicine journal

authors： Wishart HD,Reeve AM,Grant CC

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Acute coronary syndromes (ACS) management is now well informed by guidelines extrapolated from clinical trials. However, most of these data have been acquired outside the local context. We sought to describe the current patterns of ACS care in Australia. METHODS:The Acute Coronary Syndrome Prospective Audit...

journal_title：Internal medicine journal

authors： Chew DP,Amerena J,Coverdale S,Rankin J,Astley C,Brieger D

更新日期：2007-11-01 00:00:00

abstract：:It has been stated that academic medicine is in a worldwide crisis. Is this decline in hospital academic practice a predictable consequence of modern clinical practice with its emphasis on community and outpatient-based services as well as a corporate health-care ethos or does it relate to innate problems in the train...

journal_title：Internal medicine journal

authors： Wilson A

更新日期：2007-11-01 00:00:00

abstract：:Previous reports have noted an association between membranous nephropathy and focal segmental glomerulosclerosis with Guillain-Barre syndrome. We report a case of Campylobacter enteritis, which was complicated by both focal segmental glomerulosclerosis of the collapsing variety and Guillain-Barre syndrome, and propose...

journal_title：Internal medicine journal

authors： Lim A,Lydia A,Rim H,Dowling J,Kerr P

更新日期：2007-10-01 00:00:00

abstract：:A retrospective review of patients receiving rituximab off label in a large teaching hospital was conducted between July 2002 and January 2006. The indication, dosing regimen, efficacy and cost of rituximab were evaluated. Rituximab was prescribed for three clinical indications; acute organ transplant rejection, post-...

journal_title：Internal medicine journal

authors： Sharma R,Koller L,Barclay P,Liddle C

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:The association between weather and severe acute respiratory syndrome (SARS) transmission in Beijing and Hong Kong in the 2003 epidemic was studied to examine the effect of weather on SARS transmission. METHODS:Pearson's correlation analyses and negative binomial regression analyses were used to quantify th...

journal_title：Internal medicine journal

authors： Bi P,Wang J,Hiller JE

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:In Australia medical practitioners are often required to assume the responsibility for assessing fitness to drive. However the clinical practice, knowledge and attitudes of doctors with regards to this responsibility are unknown. The aim of this study was to determine the clinical practice, knowledge and att...

journal_title：Internal medicine journal

authors： Shanahan EM,Sladek RM,Phillips P

更新日期：2007-06-01 00:00:00

abstract：:The phenomenon of addiction is complex, although its expression clinically is relatively straightforward. There is a series of neurophysiological changes that mediate changes in the mesolimbic and mesocortical systems which in turn lead to disturbances in reward mechanisms. These then act to perpetuate the cycle of in...

journal_title：Internal medicine journal

authors： Foy A

更新日期：2007-05-01 00:00:00

abstract：INTRODUCTION:A generalized epidemic of HIV infection has been evolving in Papua New Guinea over the last decade, whereas in other Pacific Island countries and territories (PICT) HIV transmission has generally been less widespread. Programmes to detect HIV infection in pregnant women and to prevent mother to child trans...

journal_title：Internal medicine journal

authors： Rupali P,Condon R,Roberts S,Wilkinson L,Voss L,Thomas MG

更新日期：2007-04-01 00:00:00

abstract：:The negative health effects of the 2003 invasion of Iraq should act as a watershed in the medical profession's approach to violent conflict. ...

journal_title：Internal medicine journal

authors： Huggan PJ

更新日期：2007-04-01 00:00:00

abstract：:An 11-year-old boy presented with hepatic failure secondary to parvovirus B19 infection, requiring urgent liver transplantation. His recovery was complicated by primary Epstein-Barr virus and cytomegalovirus infections. He subsequently developed aplastic anaemia that has been refractory to antithymocyte globulin and c...

journal_title：Internal medicine journal

authors： So K,Macquillan G,Garas G,Delriviere L,Mitchell A,Speers D,Mews C,Augustson B,de Boer WB,Baker D,Jeffrey GP

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Exacerbations requiring hospital admission for chronic obstructive pulmonary disease (COPD) contribute to a decline in health status and are costly to the community. Long-term trends in admissions and associated outcomes are difficult to establish because of frequent readmissions, high case fatality and pote...

journal_title：Internal medicine journal

authors： Geelhoed EA,Brameld KJ,Holman CD,Thompson PJ

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to describe the activity of a lung cancer multidisciplinary clinic (MDC) and examine whether this model of clinical practice results in adherence to best-practice guidelines. METHODS:Prospective analysis of demographic and clinical data in 431 patients referred to a lung cancer MDC...

journal_title：Internal medicine journal

authors： Conron M,Phuah S,Steinfort D,Dabscheck E,Wright G,Hart D

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Asthma is associated with fixed airflow obstruction and an increased risk of death. The aim of this study was to relate asthma mortality and airflow obstruction to severity of asthma in a cohort of patients with chronic asthma studied over a 17-year period. METHODS:In 1980, asthma severity based on symptoms...

journal_title：Internal medicine journal

authors： Panizza JA,James AL,Ryan G,de Klerk N,Finucane KE

更新日期：2006-12-01 00:00:00

abstract：:The author, a physician in late middle age reflects on his own medical career, the aging of those who have taught him and also of those whom he has taught. He describes the sense of ennui and déjà vu. The things that seemed important as a younger doctor seem less important. He has adopted a different paradigm and has ...

journal_title：Internal medicine journal

authors： Allen RK

更新日期：2006-12-01 00:00:00